Po podaniu doustnym szybko wchłania się z przewodu pokarmowego; stężenie maksymalne uzyskiwane jest w ciągu 90–120 minut od przyjęcia preparatu. Zopiklon jest metabolizowany w wątrobie i wydalany głównie z moczem w postaci metabolitów, w niewielkim odsetku także z kałem.
If a decision is created to prescribe zopiclone concomitantly with opioids, prescribe the lowest productive dosages and minimum amount durations of concomitant use, and abide by patients carefully for indications and signs and symptoms of respiratory depression and sedation (see Section four.five Interactions with Other Medicines along with other Sorts of Interactions).
If you are going to be started out on any new medication, explain to your doctor and pharmacist you are using Imovane.
Zopiclone and/or its metabolites are excreted in breast milk so as a result shouldn't be Employed in nursing mothers.
The reason for sleeplessness need to be identified where ever possible and also the fundamental components treated just before a hypnotic is prescribed.
All medicines can have Negative effects. If you are doing working experience any Uncomfortable side effects, most of them are minimal and temporary. Even so, some Unintended effects might have professional medical awareness.
Jeżeli masz jakiekolwiek wątpliwości dotyczące stosowania preparatu, skonsultuj here się z lekarzem.
Leki uspokajające i nasenne o działaniu podobnym do benzodiazepin mogą powodować niepamięć następczą. Występuje ona najczęściej po kilku godzinach od przyjęcia leku.
Suicidal tendencies could possibly be existing and protecting actions could be necessary. As a result the bottom attainable amount of zopiclone ought to be equipped to those individuals to scale back the potential risk of intentional overdosage by the individual.
In case you overlook to take the pill before you go to mattress, and you also wake up late while in the night time or pretty early in the morning, tend not to choose it.
Get in touch with your doctor straight absent, or go straight towards the Emergency Department at your closest medical center in the event you recognize any of these significant side effects.
Helsedirektoratet anbefaler at vanedannende sovemidler ikke brukes mer enn to til fireplace uker og oppfordret i 2014 leger og pasienter til økt varsomhet i bruken av disse midlene. Mennesker som bruker slike midler hver kveld about lang tid, sovner ikke raskere, sover ikke mer og fileøler seg ikke mer opplagte enn dem som lar være å bruke sovepiller til tross for at de har søvnproblemer.
Et teoretisk volum som beskriver hvordan et legemiddel fordeler seg i vev og blodbane. Ved et lavt distribusjonsvolum fordeler legemiddelet seg i liten grad utenfor blodbanen.
Anterograde amnesia may well occur, specially when rest is interrupted or when retiring to mattress is delayed after the consumption from the pill.